Percentage wise Eyam suffered a higher death toll than of London. 260 Eyam villagers died over the 14 months of the plague out of a total population of 800 and 76 families were affected by the plague.
However, their quick thinking to bury the dead as close to where they died as possible, stop people entering or leaving the village and leaving money for foods and medicines in a well of vinegar to kill off the disease turned out to be a selfless act which stopped the plague travelling to the nearby towns and cities.
These actions have never been forgotten by the village and we have dug out pictures from the archive showing the how people allow the memories of those who died to live on.
Take a look and see who you can spot dressing up, or walking the carnival.
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1. How the plague victims' selflessness is never forgotten
How the plague victims' selflessness is never forgotten Photo: Jason Chadwick
2. Sacrifice honoured
A museum opened in Eyam, chronicling the story of the village and how it declared a period of quarantine when it became a victim of the bubonic plague.
The secretary of the Eyam Musuem, Geoff Ward, is pictured back in 1994, with one of the displays, showing the first plague victim, George Viccars, in the background Photo: YPN
3. Practising their parts
Heather Hatton, Amy Vickers and Joshua Hassop practiced their parts for the story of the Eyam Plague at St Andrews School in Dronfield which will be performed at the Millenium Dome in 2000 Photo: DEAN ATKINS
4. Plague cottage
One of the Plague Cottages, Eyam, pictured in 2004 Photo: submitted